FIRMNESS

Retinol + Aloe

An Elixir of Life for your skin


Dark spots, loss of elasticity, dull skin? Give your skin a new life. 

BIOMIMIC™ Retinol + Aloe is a firming booster serum. 


This serum is formulated with high strength Retinol (Vitamin A) and a cocktail of potent vitamins and ceramides to combat the most common signs of ageing.

  • High-strength 1% retinol concentration

  • Fights against the signs of aging, helps reduce the appearance of wrinkles & fine lines

  • Skin is firmer and more radiant

  • Helps fight against free radicals and fade sun spots, for a brighter looking skin

  • Use at night after cleansing & exfoliating. 

SKIN TYPES

DRY, NORMAL, OILY, COMBINATION

SKIN CONDITION

AGEING

$69.00

  • INGREDIENTS
  • HOW TO USE
  • BIOMIMICRY
  • THE SCIENCE

Key Ingredients and Benefits

BIOMIMIC™ Retinol + Aloe helps slow down the aging process, triggered by UV-radiation exposure and internal aging with increased elastin formation. The degradation of collagen with time also plays a role in making it elastic. 


Cells undergo DNA damage due to repeated divisions and lose this ability altogether. These changes appear as damaged and wrinkled skin over time.

BIOMIMIC™ Retinol + Aloe booster is packed with the following key ingredients;

Retinyl Palmitate 1%: Skin Benefit

1.

WHY DID WE USE IT:

Is an ester form of vitamin A and is naturally found in the epidermis of the skin. BIOMIMIC™ Retinol + Aloe serum uses this form because;


  • It has stable preparation and a high molecular weight
  • Unlike retinoid acid, it does not irritate the skin
  • It has high consumer adoptability due to its skin-friendly nature

Dark green plants contain carotenoids that are provitamins and are converted into Retinol. Research shows that topical application of the ester derivative of vitamin A results in collagen increase and thickening of the epidermis (1).

2.

Retinyl Palmitate 1% effectively penetrates the epidermis and binds to specific receptors. It modulates the DNA sequence of the gene that controls keratinocytes’ division (1, 3). 

3.

Retinyl Palmitate 1% reduces DNA damage by increasing cell division, leading to healthier collagen formation.

  • SKIN BENEFITS:

  • Helps promote cellular turnover by replacing ageing cells with new healthy cells
  • Helps reduce the appearance of fine lines & wrinkles
  • Improves uneven skin tone & smooths skin
  • Improves skin firmness and elasticity

Ceramides & Phytosphingosine Skin Benefit

1.

WHY DID WE USE IT:

Ceramides are lipid molecules that help strengthen the barrier function of the skin and protect it from environmental stressors. Ceramides retain the moisture content of the extracellular matrix. They prevent water loss across the lipid layer present in the stratum corneum layer of the epidermis which provides a moisturizing effect on the skin.

  • SKIN BENEFIT:

  • Helps strengthen the skin barrier for healthy looking skin
  • Helps prevent water loss and provide a lasting moisturising effect 
  • Helps reduce the appearance of fine lines & wrinkles

Vitamin B5 Skin Benefit

1.

WHY DID WE USE IT:

Vitamin B5 is a derivative of pantothenic acid and helps in the formation of collagen in the skin. High concentrations are found in Shiitake Mushrooms.

2.

Vitamin B5 in BIOMIMIC™ Retinol + Aloe increases the level of procollagen 4a2 Growth Factor in fibroblasts. Since fibroblasts produce collagen, their growth factor stimulation boosts its formation (5).

  • SKIN BENEFITS:

  • Improves skin firmness and elasticity
  • Helps strengthen the skin barrier for healthy looking skin
  • Helps reduce UV-induced skin damage

Vitamin E Skin Benefit

1.

WHY DID WE USE IT:

Vitamin E is one of the most powerful known antioxidants shown to reduce oxidative stress. Vitamin E plays a role in the physiological processes related to the growth, photo-protection, blooming, longevity and senescence of plants. High concentrations are found in nuts and seeds.


2.

Vitamin E inhibits the activity of matrix metalloproteinases (MMP), especially MMP-1 (5). These are groups of collagenase enzymes that degrade collagen in your body. Their inhibition preserves collagen in the extracellular matrix.

  • SKIN BENEFITS:

  • Improves skin firmness and elasticity
  • Helps reduce UV-induced skin damage
  • Helps prevent collagen degradation therefore reduce the signs of ageing

How to use:

BIOMIMIC™ Retinol + Aloe is best applied at night, every second day as a last step to your skincare routine.


Dispense 2 pumps into the palm of your hand and then apply to your face.


Add another 2 pumps if you will also be applying to your neck and chest.

USAGE

  • PM

The Science of Biomimicry

Your cells experience senescence with each division. It is a fancy name for biological aging, and your genetic code determines this phenomenon. Skin cells lose their ability to regenerate with aging as well. The appearance of fine lines is a common symptom of it. Once they set in, wrinkling becomes just a matter of time. It is an inevitable and unavoidable effect of skin aging. But is it, really?


Many organisms in nature don’t age at all. They exhibit negligible or negative senescence and live for centuries. Ever heard of fish belonging to group Hydra? These fish have a potent regenerative ability because their cell proliferation has no genetic limitations. New cells replace the older ones frequently, and these fish appear to be biologically immortal.


BIOMIMIC™ Retinol + Aloe serum mimics this ability of hydra fish and converts it into a skin serum. It has ingredients that promote cell differentiation and strengthen the extracellular matrix. The biomimetic properties of BIOMIMIC™ Retinol + Aloe helps slow down the aging process by altering the genetic expression. It enhances the shedding of old cells and replaces them with new ones.


Effects on Genetic Expression

The secret to smooth and youthful skin is in the preservation of collagen and other extracellular matrix proteins. The extracellular matrix contains water, collagen, and various other polysaccharides. 


Ingredients like those found in BIOMIMIC™ Retinol + Aloe are designed to strengthen the extracellular matrix by boosting new collagen synthesis and inhibiting its degradation.


References

1. Oliveira, M. B., do Prado, A. H., Bernegossi, J., Sato, C. S., Lourenço Brunetti, I., Scarpa, M. V., Leonardi, G. R., Friberg, S. E., & Chorilli, M. (2014). Topical application of retinyl palmitate-loaded nanotechnology-based drug delivery systems for the treatment of skin aging.BioMed research international, 2014, 632570. 


2. Zasada, M., & Budzisz, E. (2019). Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments.Postepy dermatologii i alergologii, 36(4), 392–397. 


3. Sorg, O., Kuenzli, S., Kaya, G., & Saurat, J. H. (2005). Proposed mechanisms of action for retinoid derivatives in the treatment of skin aging.Journal of cosmetic dermatology, 4(4), 237–244.


4. Hantke, B., Lahmann, C., Venzke, K., Fischer, T., Kocourek, A., Windsor, L. J., Bergemann, J., Stäb, F., & Tschesche, H. (2002). Influence of flavonoids and vitamins on the MMP- and TIMP-expression of human dermal fibroblasts after UVA irradiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 1(10), 826–833.


5. Kim, S., Hong, I., Hwang, J. S., Choi, J. K., Rho, H. S., Kim, D. H., Chang, I., Lee, S. H., Lee, M. O., & Hwang, J. S. (2006). Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin.Molecular medicine (Cambridge, Mass.), 12(1-3), 17–24.


6. Kobayashi, D., Kusama, M., Onda, M., & Nakahata, N. (2011). The effect of pantothenic acid deficiency on keratinocyte proliferation and the synthesis of keratinocyte growth factor and collagen in fibroblasts.Journal of pharmacological sciences, 115(2), 230–234.