Anti-wrinkle
Improvesskin barrier
Collagenbuilder
Improvestexture
Anti-wrinkle
- Improves skin barrier
- Collagen builder
- Improves texture
- INGREDIENTS
- HOW TO USE
- BIOMIMICRY
- THE SCIENCE
Key ingredients
Skin cells undergo constant DNA damage that is caused by free radicals. To help repair the damage cells are designed to rebuild and duplicate. Unfortunately as we age the bodies ability to duplicate cells slows down.
Ingredients found within BIOMIMIC™ Retinol + Aloe can help re-stimulate cellular production and turnover.
Retinyl Palmitate 1%
It is an ester form of vitamin A and is naturally found in the epidermis of the skin. BIOMIMIC™ Retinol + Aloe serum uses this form because:
• It has stable preparation and a high molecular weight
• Unlike retinoid acid, it does not irritate the skin
Dark green plants contain carotenoids - its what gives plants their color. The carotenoids are also provitamins and are converted into Retinol. Research shows that topical application of the ester derivative of vitamin A results in an increase of collagen as well as thickening of the epidermis (1).
Retinyl Palmitate 1% has been shown to effectively penetrate the epidermis and activate genes responsible collagen synthesis (1, 3).
Retinyl Palmitate 1% helps reduce DNA damage by increasing cell division, leading to healthier collagen formation.
Improves skin firmness and elasticityImproves uneven skin tone & smooths skin
Helps reduce the appearance of fine lines & wrinkles
Helps promote cellular turnover by replacing ageing cells with new healthy cells
Dark green plants produce higher concentrations of Vitamin A
Ceramides & Phytosphingosine
Ceramides are lipid molecules that help strengthen the skin barrier. A strong skin barrier is essential in protecting the skin from environmental stressors. Ceramides work to retain moisture content, prevent water loss and provides a moisturizing effect on the skin.
- Helps reduce the appearance of fine lines & wrinkles
Helps strengthen the skin barrier for healthy looking skin
Helps prevent water loss and provide a lasting moisturising effect
Vitamin B5
Vitamin B5 is a derivative of pantothenic acid and helps in the formation of collagen in the skin
Vitamin B5 is formulated to help boost keratinocyte growth factors which are the main type of cell found in the epidermis.(3).
- Improves skin firmness and elasticity
Moisturising effect on the skin
Helps prevent transdermal water loss
Helps strengthen the skin barrier for healthy looking skin
Smooths and softens the skin for a supple, wrinkle-free appearance
High concentrations are found naturally in Shiitake Mushrooms
Vitamin E
Vitamin E is one of the most powerful known antioxidants shown to reduce oxidative stress. Vitamin E plays a role in the photo-protection, longevity by slowing down the cellular aging process.
Vitamin E helps reduce the activity of matrix metalloproteinases (MMP) (5). MMPs are groups enzymes that degrade collagen in your skin.
- Improves skin firmness and elasticity
Helps reduce UV-induced skin damage
Helps prevent collagen degradation to reduce the signs of ageing
High concentrations of Vitamin E are found naturally in nuts and seeds.
Directions
BIOMIMIC™ Retinol + Aloe is best applied every second night as a last step to your skincare routine.
The science of
biomimicry
Plant cells experience senescence with each division. Senescence is the name used for biological aging. Our skin also experiences senescence, and overtime our skin cells can lose their ability to regenerate. The appearance of fine lines and laxity are common symptoms.
Many organisms in nature don’t age at all. They exhibit negative senescence and can live for centuries. Ever heard of fish belonging to group Hydra? These fish have a potent regenerative ability. New cells replace the older ones at such a rapid rate that these fish appear to be biologically immortal.
While we cant live forever (yet) BIOMIMIC™ Retinol + Aloe mimics the ability of faster cellular regeneration. It has ingredients that promote cell differentiation and strengthens the skin support structures.
The biomimetic properties of BIOMIMIC™ Retinol + Aloe helps to slow down the aging process by increasing the shedding of older cells and replacing them with new ones.
Effects on genetic expression
The secret to smooth and youthful skin is in the preservation of collagen and other extracellular matrix proteins. The extracellular matrix contains water, collagen, and various other polysaccharides.
Ingredients like those found in BIOMIMIC™ Retinol + Aloe are designed to strengthen the extracellular matrix by boosting new collagen synthesis and slows down its degradation.
References
1. Oliveira, M. B., do Prado, A. H., Bernegossi, J., Sato, C. S., Lourenço Brunetti, I., Scarpa, M. V., Leonardi, G. R., Friberg, S. E., & Chorilli, M. (2014). Topical application of retinyl palmitate-loaded nanotechnology-based drug delivery systems for the treatment of skin aging. BioMed research international, 2014, 632570.
2. Zasada, M., & Budzisz, E. (2019). Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments .Postepy dermatologii i alergologii, 36(4), 392–397.
3. Sorg, O., Kuenzli, S., Kaya, G., & Saurat, J. H. (2005). Proposed mechanisms of action for retinoid derivatives in the treatment of skin aging. Journal of cosmetic dermatology, 4(4), 237–244.
4. Hantke, B., Lahmann, C., Venzke, K., Fischer, T., Kocourek, A., Windsor, L. J., Bergemann, J., Stäb, F., & Tschesche, H. (2002). Influence of flavonoids and vitamins on the MMP- and TIMP-expression of human dermal fibroblasts after UVA irradiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 1(10), 826–833.
5. Kim, S., Hong, I., Hwang, J. S., Choi, J. K., Rho, H. S., Kim, D. H., Chang, I., Lee, S. H., Lee, M. O., & Hwang, J. S. (2006). Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin. Molecular medicine (Cambridge, Mass.), 12(1-3), 17–24.
6. Kobayashi, D., Kusama, M., Onda, M., & Nakahata, N. (2011). The effect of pantothenic acid deficiency on keratinocyte proliferation and the synthesis of keratinocyte growth factor and collagen in fibroblasts. Journal of pharmacological sciences, 115(2), 230–234.
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